Trying to piece together his memories and determine who wanted him dead, he began to work as a shadowrunner. Jake is a rare shaman with cyberware, because he had it implanted before discovering his calling as a Dog Shaman.
He discovered that his head not only contained a bomb, but also crucial data he carried as a courier without his knowledge. This data was a program designed to kill a malevolent artificial intelligence created and protected by Drake and Aneki Corporation.
In 2054, he assisted a fellow shadowrunner in investigating the Ripper killings in Seattle.
While the plot of the video game he appeared in was loosely adapted from Robert Charrette's novel Never Deal With a Dragon, the name "Armitage" is a reference to a character from William Gibson's novel, Neuromancer, written in 1981 and possibly the most influential book in the Cyberpunk genre. However Jake Armitage more closely resembles the main protagonist in Neuromancer: Henry Case.