The DeLuca Family was based in the city of Chicago.
The DeLuca family was the 2nd largest Mafia family in Chicago prior to the bug infestation of 2055 which turned Chicago into "Bug City". It controlled drugs, money laundering, prostitution, and smuggling in the city. They were led by Angelo "Copdrop" DeLuca, who earned his moniker by tossing an Eagle Security Lieutenant out of a skyscraper.
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- Shadowrun 2050, 84